when you get this message using the new 'validate product' option then normally you check your certificates and provisioning profiles and you'll find your mistake. this time i double, triple, and quadruple checked these things and could not find anything odd.
a long search in the apple developer forums revealed that there is an issue with code signing when you installed the beta of the iPhone SDK4 in another location. after installing the current release sdk over the existing one everything works fine again.
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